International Journal of Keratoconus and Ectatic Corneal Diseases

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VOLUME 2 , ISSUE 3 ( September-December, 2013 ) > List of Articles

RESEARCH ARTICLE

Case of Corneal Perforation as a Complication after Uneventful CXL without Infection

Goktug Demirci, Akif Ozdamar

Citation Information : Demirci G, Ozdamar A. Case of Corneal Perforation as a Complication after Uneventful CXL without Infection. Int J Kerat Ect Cor Dis 2013; 2 (3):139-142.

DOI: 10.5005/jp-journals-10025-1067

Published Online: 01-12-2016

Copyright Statement:  Copyright © 2013; The Author(s).


Abstract

Purpose

To demonstrate that UVA/riboflavin crosslinking (CXL) can cause corneal melting in some unpredictable cases.

Materials and methods

We will present a case report of 25-year-old male patient referred for emergency keratoplasty which is due to corneal melting and perforation developed after uneventful CXL procedure for the treatment of keratoconus.

Results

We performed uncomplicated penetrating keratoplasty of the left eye in our hospital.

Conclusion

CXL is gradually becoming the standard treatment procedure for progressive keratoconus and the only major safety concerns associated with CXL are ocular surface damage and endothelial cell damage. This case has shown, however, that even if CXL seems to have been successful, there is still a risk of adverse outcomes. Our report suggests that further research is necessary regarding the safety of corneal collagen crosslinking in corneas with keratoconus.

How to cite this article

Demirci G, Ozdamar A. Case of Corneal Perforation as a Complication after Uneventful CXL without Infection. J Kerat Ect Cor Dis 2013;2(3):139-142.


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  1. Keratoconus and related noninflammatory corneal thinning disorders. Surv Ophthalmol 1984;28:293-322.
  2. Collagen crosslinking in keratoconus. Invest Ophthalmol Vis Sci 1978;17:63-65.
  3. Increased rigidity of the cornea caused by intrastromal crosslinking. Ophthalmology 1997;94:902-906.
  4. Permanent corneal haze after riboflavin-UVA-induced crosslinking in keratoconus. J Refract Surg 2009;25:824-828.
  5. Keratitis and corneal scarring after UVA/riboflavin crosslinking for keratoconus. J Refract Surg 2009;25:819-823.
  6. Microbial keratitis after corneal collagen crosslinking. J Cataract Refract Surg 2009;35:1138-1140.
  7. Keratoconus. Surv Ophthalmol 1998 Jan-Feb; 42:297-319.
  8. Corneal crosslinking and safety issues. Open Ophthalmol J 2011;11:14-16.
  9. Increased resistance of riboflavin/ultraviolet: a treated cornea against enzymatic digestion. Curr Eye Res 2004;29:35-40.
  10. Intraocular pressure measurements after corneal collagen crosslinking with riboflavin and ultraviolet A in eyes with keratoconus. J Cataract Refract Surg 2010;36:1724-1727.
  11. Complications of corneal collagen crosslinking. J Ophthalmol 2011; Available at: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3255294/
  12. Acanthamoeba keratitis with perforation after corneal crosslinking and bandage contact lens use. J Cataract Refract Surg 2009;35:788-791.
  13. Corneal infiltrates after corneal collagen crosslinking. J Refract Surg 2010;26:609-611.
  14. Diclofenac-induced acute corneal melt after collagen crosslinking for keratoconus. Cornea 2010;29:117-119.
  15. Corneal melting in both eyes after simultaneous corneal crosslinking in a patient with keratoconus and Down syndrome. Ophthalmology 2010;107:951-955.
  16. Journal of Medical Case Reports 2011;5:152. Available at: http://www.jmedicalcasereports.com/content/5/1/152.
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