International Journal of Keratoconus and Ectatic Corneal Diseases

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VOLUME 1 , ISSUE 1 ( January-April, 2012 ) > List of Articles

RESEARCH ARTICLE

The Epidemiology and Etiology of Keratoconus

Ariela Gordon-Shaag, Michel Millodot, Einat Shneor

Citation Information : Gordon-Shaag A, Millodot M, Shneor E. The Epidemiology and Etiology of Keratoconus. Int J Kerat Ect Cor Dis 2012; 1 (1):7-15.

DOI: 10.5005/jp-journals-10025-1002

Published Online: 01-04-2012

Copyright Statement:  Copyright © 2012; Jaypee Brothers Medical Publishers (P) Ltd.


Abstract

How to cite this article

Gordon-Shaag A, Millodot M, Shneor E. The Epidemiology and Etiology of Keratoconus. Int J Keratoco Ectatic Corneal Dis 2012;1(1):7-15.


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  1. Keratoconus. Surv Ophthalmol 1998;42: 297-319.
  2. Keratoconus and related noninflammatory corneal thinning disorders. Surv Ophthalmol 1984;28:293-322.
  3. Prognostic factors for the progression of keratoconus. Ophthalmology 1994;101:439-47.
  4. Superior keratoconus. Cornea 1997;16:693-94.
  5. Unilateral keratoconus. Incidence and quantitative topographic analysis. Ophthalmology 1997;104:1409-13.
  6. Longitudinal study of the normal eyes in unilateral keratoconus patients. Ophthalmology 2004;111:440-46.
  7. Estimation of patient visit rate and incidence of keratoconus in the 23 wards of Tokyo. Nihon Ganka Gakkai Zasshi 2002;106:365-72.
  8. Baseline factors predictive of incident penetrating keratoplasty in keratoconus. Am J Ophthalmol 2006;142:923-30.
  9. Clinical and epidemiological features of keratoconus genetic and external factors in the pathogenesis of the disease. Acta Ophthalmol Suppl 1986;178:1-64.
  10. Corneal scarring in the collaborative longitudinal evaluation of keratoconus (CLEK) study: Baseline prevalence and repeatability of detection. Cornea 1999;18:34-46.
  11. Repeatability and agreement of two corneal-curvature assessments in keratoconus: Keratometry and the first definite apical clearance lens (FDACL). CLEK study group. Collaborative longitudinal evaluation of keratoconus. Cornea 1998;17:267-77.
  12. Baseline findings in the collaborative longitudinal evaluation of keratoconus (CLEK) study. Invest Ophthalmol Vis Sci 1998;39:2537-46.
  13. Automated keratoconus screening with corneal topography analysis. Invest Ophthalmol Vis Sci 1994;35:2749-57.
  14. Computer-assisted corneal topography. High- resolution graphic presentation and analysis of keratoscopy. Invest Ophthalmol Vis Sci 1984;25:1426-35.
  15. Corneal topography of early keratoconus. Am J Ophthalmol 1989;108:107-12.
  16. KISA% index: A quantitative videokeratography algorithm embodying minimal topographic criteria for diagnosing keratoconus. J Cataract Refract Surg 1999;25:1327-35.
  17. Zernike polynomial fitting fails to represent all visually significant corneal aberrations. Invest Ophthalmol Vis Sci 2003;44:4676-81.
  18. Clinical management of keratoconus. A multicenter analysis. Ophthalmology 1990;97:433-45.
  19. Biomicroscopic signs and disease severity in keratoconus. Collaborative longitudinal evaluation of keratoconus (CLEK) study group. Cornea 1996;15:139-46.
  20. Keratoconus clinical findings according to different age and gender groups. Cornea 2008;27:1109-13.
  21. Keratoconus and obesity— a connection. Invest Ophthalmol Vis Sci 2003;44:812-B787.
  22. Where are the older keratoconus patients? Cornea 2009;28:836.
  23. Incidence and severity of keratoconus in Asir province, Saudi Arabia. Br J Ophthalmol 2005;89:1403-06.
  24. Epidemiology of keratoconus in the Urals. Vestn Oftalmol 1998;114:38-40.
  25. Prevalence and associations of keratoconus in rural Maharashtra in central India: The central India eye and medical study. Am J Ophthalmol 2009;148: 760-65.
  26. A keratoscopic survey of 13,395 eyes. Am J Optom Arch Am Acad Optom 1959;36:3-11.
  27. A 48-year clinical and epidemiologic study of keratoconus. Am J Ophthalmol 1986;101:267-73.
  28. Incidence and prevalence of keratoconus in Denmark. Acta Ophthalmol Scand 2007;85:890-92.
  29. Epidemiology of keratoconus and corneal topography in normal young male subjects. Invest Ophthalmol Vis Sci 1995;36:S307.
  30. Prevalence and associated factors of keratoconus in Jerusalem: A cross-sectional study. Ophthalmic Epidemiol 2011;18:91-97.
  31. Atopy and keratoconus: A multivariate analysis. Br J Ophthalmol 2000;84:834-36.
  32. Keratoconus and its prevalence in Macedonia. Macedonian Journal of Medical Sciences 2011;2:58-62.
  33. A profile of keratoconus in New Zealand. Cornea 2003;22:122-25.
  34. Does ethnic origin influence the incidence or severity of keratoconus? Eye (Lond) 2000;14(Pt 4):625-28.
  35. Genetic epidemiological study of keratoconus: Evidence for major gene determination. Am J Med Genet 2000;93:403-09.
  36. The Dundee University Scottish keratoconus study: Demographics, corneal signs, associated diseases, and eye rubbing. Eye (Lond) 2008;22: 534-41.
  37. Influence of ethnic origin on the incidence of keratoconus and associated atopic disease in Asians and white patients. Eye (Lond) 2004;18:379-83.
  38. Prevalence of keratoconus patients in Japan. Nihon Ganka Gakkai Zasshi 1985;89:407-11.
  39. Computerized corneal tomography and associated features in a large New Zealand keratoconic population. J Cataract Refract Surg 2011;37:1493-501.
  40. Consanguinity among the Arab and Jewish populations in Israel. Pediatr Endocrinol Rev 2006;3 Suppl 3:437-46.
  41. The genetics of keratoconus. Ophthalmol Clin North Am 2003;16:607-20
  42. The role of heredity in keratoconus. Trans Ophthalmol Soc Aust 1968;27:52-54.
  43. Keratoconus in two pairs of identical twins. Cornea 1996;15:90-93.
  44. Discordance for keratoconus in two pairs of monozygotic twins. Cornea 1999;18:444-51.
  45. The variable expression of keratoconus within monozygotic twins: Dundee University Scottish Keratoconus Study (DUSKS). Cont Lens Anterior Eye 2006;29:123-26.
  46. Association between keratoconus and atopy. Br J Ophthalmol 1989;73:816-22.
  47. Videokeratography of keratoconus in monozygotic twins. J Refract Surg 1996;12: 180-83.
  48. Identity-by-descent approach to gene localisation in eight individuals affected by keratoconus from north-west Tasmania, Australia. Hum Genet 2002;110:462-70.
  49. Mutation altering the miR-184 seed region causes familial keratoconus with cataract. Am J Hum Genet 2011;89:628-33.
  50. Three VSX1 gene mutations, L159M, R166W, and H244R are not associated with keratoconus. Cornea 2008;27:189-92.
  51. A locus for autosomal dominant keratoconus: Linkage to 16q22.3-q23.1 in Finnish families. Invest Ophthalmol Vis Sci 2002;43:3160-64.
  52. Mutational screening of VSX1 in keratoconus patients from the European population. Eye (Lond) 2010;24:1085-92.
  53. VSX1: A gene for posterior polymorphous dystrophy and keratoconus. Hum Mol Genet 2002;11:1029-36.
  54. A genome-wide association study identifies a potential novel gene locus for keratoconus, one of the commonest causes for corneal transplantation in developed countries. Hum Mol Genet 2011.
  55. Association of polymorphisms in the hepatocyte growth factor gene promoter with keratoconus. Invest Ophthalmol Vis Sci 2011;52:8514-19.
  56. Biometric measurements of the eyes in teenagers and young adults with Down syndrome. Acta Ophthalmol Scand 2001;79:616-25.
  57. Computerized corneal topography in a paediatric population with Down syndrome. Clin Experiment Ophthalmol 2005;33:47-52.
  58. Leber congenital amaurosis and its association with keratoconus and keratoglobus. J Pediatr Ophthalmol Strabismus 1994;31:38-40.
  59. Leber Congenital Amaurosis 1993.
  60. Keratoconus and the Ehlers-Danlos syndrome: A new aspect of keratoconus. Med J Aust 1975;1:571-73.
  61. The cornea in connective tissue diseases. Ophthalmology 1978;85:1014-17.
  62. The eye in the Marfan syndrome. Trans Am Ophthalmol Soc 1981;79:684-733.
  63. Blue sclerae and keratoconus: Key features of a distinct heritable disorder of connective tissue. Clin Genet 1973;4:8-16.
  64. Mongolism (Down's syndrome) and keratoconus. Br J Ophthalmol 1963;47:321-30.
  65. A syndrome of hypogonadism, alopecia, diabetes mellitus, mental retardation, deafness, and ECG abnormalities. J Med Genet 1983;20:216-19.
  66. Mechanisms of rubbing-related corneal trauma in keratoconus. Cornea 2009;28:607-15.
  67. Keratoconus: A review. Cont Lens Anterior Eye 2010;33: 157-66.
  68. On the location of the cone and the etiology of keratoconus. Cornea 1995;14:142-43.
  69. Asymmetric keratoconus attributed to eye rubbing. Cornea 2004;23:560-64.
  70. Keratoconus, allergy, itch, eye- rubbing and hand-dominance. Clin Exp Optom 2003;86: 376-84.
  71. Between-eye asymmetry in keratoconus. Cornea 2002;21:671-79.
  72. Keratoconus and acute hydrops in mentally retarded patients with congenital rubella syndrome. Am J Ophthalmol 1981;91:231-33.
  73. Acute hydrops in the corneal ectasias: Associated factors and outcomes. Trans Am Ophthalmol Soc 1999;97:187-98.
  74. Keratoconus and corneal hydrops associated with compulsive eye rubbing. Refract Corneal Surg 1993;9:383-84.
  75. Keratoconus caused by eye rubbing in patients with Tourette syndrome. Can J Ophthalmol 2011;46:83-86.
  76. A case of bilateral self-induced keratoconus in a patient with Tourette syndrome associated with compulsive eye rubbing: Case report. BMC Ophthalmol 2011;11:28.
  77. Keratoconus and eye rubbing. Am J Ophthalmol 1984;97:527-28.
  78. Keratoconus and ocular massage. Am J Ophthalmol 1988;106:757-58.
  79. Keratoconus and coexisting atopic disease. Br J Ophthalmol 1977;61:761-64.
  80. Preliminary note on the psychological and mental status of patients with keratoconus. Bull Soc Ophtalmol Fr 1980;80:441-43.
  81. Eczema and keratoconus. Br Med J 1965;2: 977-79.
  82. Personality trends in keratoconus. An analysis. Arch Ophthalmol 1987;105:798-800.
  83. Personality and keratoconus. CLAO J 1990;16:62-64.
  84. Keratoconus and atopic diseases. Ann Ophthalmol 1978;10:991-94.
  85. Evaluation of the corneal topographic characteristics of keratoconus with orbscan II in patients with and without atopy. Cornea 2007;26:945-48.
  86. Atopy and keratoconus. Am J Ophthalmol 1958;45:904-06.
  87. The natural history of atopic dermatitis. A 20-year follow-up study. Arch Dermatol 1964;89:209-14.
  88. A study of the occurrence of atopic traits in patients with keratoconus. J Allergy 1970;46:32-39.
  89. The association of keratoconus with immune disorders. Cornea 2010;29:1261-64.
  90. Evidence of oxidative stress in human corneal diseases. J Histochem Cytochem 2002;50: 341-51.
  91. The cascade hypothesis of keratoconus. Cont Lens Anterior Eye 2003;26(3):139-46.
  92. Superoxide dismutase isoenzymes in the normal and diseased human cornea. Invest Ophthalmol Vis Sci 2001;42:2293-96.
  93. The expression of Fas ligand protein in ultraviolet-exposed rabbit corneas. Cornea 2002;21:91-94.
  94. Ultraviolet radiation-induced corneal degeneration in 129 mice. Toxicol Pathol 2007;35:819-26.
  95. The human cornea has a high incidence of acquired chromosome abnormalities. Hum Genet 1997;101:26-29.
  96. Collagen cross-linking: A new treatment paradigm in corneal disease—a review. Clin Experiment Ophthalmol 2010;38:141-53.
  97. Cigarette smoking is negatively associated with keratoconus. J Refract Surg 2008;24:S737-40.
  98. Videokeratography of the fellow eye in unilateral keratoconus. Ophthalmology 1993;100:181-86.
  99. The molecular genetics of retinoblastoma. Cancer Surv 1990;9:529-54.
  100. Life expectancy in keratoconus. Br J Ophthalmol 1992;76:590-91.
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