International Journal of Keratoconus and Ectatic Corneal Diseases

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VOLUME 7 , ISSUE 1 ( 2018 ) > List of Articles

REVIEW ARTICLE

Can We diagnose Keratoconus by evaluating Tear Sample?

Burcu Nurözler Tabakcý, Aylin Kýlýç, Mustafa Eliaçýk

Keywords : Biomarkers, Keratoconus, Tear fluid.

Citation Information : Tabakcý BN, Kýlýç A, Eliaçýk M. Can We diagnose Keratoconus by evaluating Tear Sample?. Int J Kerat Ect Cor Dis 2018; 7 (1):31-34.

DOI: 10.5005/jp-journals-10025-1157

License: CC BY-SA 3.0

Published Online: 01-06-2018

Copyright Statement:  Copyright © 2018; Jaypee Brothers Medical Publishers (P) Ltd.


Abstract

Keratoconus (KC) is the most common corneal ectatic disorder characterized by asymmetric cone-shaped corneal protrusion. The pathophysiology of KC is still unclear. For many years, KC has been considered as a noninflammatory degenerative disease. However, several studies suggested that inflammatory mediators play a role in KC pathogenesis. Tear film contains various mediators that reflect ocular surface diseases. Monitoring the changes in tear composition can be used as a diagnostic tool. In this review, the adequacy of tear markers in the diagnosis of KC was discussed.


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