International Journal of Keratoconus and Ectatic Corneal Diseases

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VOLUME 1 , ISSUE 2 ( May-August, 2012 ) > List of Articles

RESEARCH ARTICLE

Validation of a New Scoring System for the Detection of Early Forme of Keratoconus

Alain Saad

Citation Information : Saad A. Validation of a New Scoring System for the Detection of Early Forme of Keratoconus. Int J Kerat Ect Cor Dis 2012; 1 (2):100-108.

DOI: 10.5005/jp-journals-10025-1019

Published Online: 00-08-2012

Copyright Statement:  Copyright © 2012; Jaypee Brothers Medical Publishers (P) Ltd.


Abstract

Purpose

To evaluate the accuracy of a new objective method for the detection of ectasia susceptible eyes.

Methods

One hundred and eighty-three elevation and placido topographies were retrospectively evaluated by one experimented refractive surgeon and classified as ‘normal’ or ‘at risk for LASIK’. An objective automated system built on the combination of topography and tomography data in a discriminant function was also used to classify the corneas. The concordance between the objective and the subjective classification was evaluated and the usefulness of the objective scoring system was assessed by receiver operating characteristic (ROC) curve analysis.

Results

The mean age of the studied group was 37 ± 8 years old. One hundred and fifty-nine eyes were subjectively classified as ‘normal’ and 24 as ‘At risk for LASIK’. The scoring system correctly classified 153 eyes as ‘normal’ and 22 eyes as ‘at risk for LASIK’. Six eyes were wrongly detected as ‘at risk’ by the automated system (false-positive) and two eyes were wrongly classified as ‘normal’ (false-negative). The sensitivity and specificity of the automated system were 92 and 96% respectively.

Conclusion

An automated system built on the combination of topography and tomography parameters can help in creating a sensitive and specific artificial intelligence for the detection of corneas at risk for refractive surgery.

How to cite this article

Saad A, Gatinel D. Validation of a New Scoring System for the Detection of Early Forme of Keratoconus. Int J Kerat Ect Cor Dis 2012;1(2):100-108.


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