International Journal of Keratoconus and Ectatic Corneal Diseases

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VOLUME 1 , ISSUE 2 ( May-August, 2012 ) > List of Articles

RESEARCH ARTICLE

Biomechanical and Refractive Results of Transepithelial Cross-linking Treatment in Keratoconic Eyes

Cynthia J Roberts

Citation Information : Roberts CJ. Biomechanical and Refractive Results of Transepithelial Cross-linking Treatment in Keratoconic Eyes. Int J Kerat Ect Cor Dis 2012; 1 (2):75-78.

DOI: 10.5005/jp-journals-10025-1015

Published Online: 00-08-2012

Copyright Statement:  Copyright © 2012; Jaypee Brothers Medical Publishers (P) Ltd.


Abstract

Purpose

To analyze change in visual acuity (VA), refractive outcomes, corneal compensated intraocular pressure (IOPcc), corneal hysteresis (CH) and cornea resistance factor (CRF) after transepithelial cross-linking (CXL) treatment.

Setting

Kudret Eye Hospital, Ankara, Turkey

Materials and methods

A total of 32 eyes of 22 patients diagnosed with keratoconus were included in this retrospective study. Changes in VA, spheric and cylinderic refraction for all eyes were analyzed before and 3 months after transepithelial CXL. In addition, a subset of 14 eyes had data acquired using the ocular response analyzer (ORA), and for these eyes, IOPcc, CH and CRF were recorded as well as a measurement of the amplitude of the first peak in the infrared signal (peak 1), used to identify the inward applanation event. The ORA parameters were also compared before and 3 months after treatment.

Results

Uncorrected and best corrected VA increased 1.76 and 1.61 Snellen lines (p < 0.05); spheric and cylinderic refractions improved 0.74 and 0.43 D (p > 0.05) respectively. Mean changes in IOPcc, CRF and CH were not significantly different (p > 0.05). However, mean peak 1 signal value increased significantly (p < 0.05).

Conclusion

Transepithelial CXL is effective in VA improvement in the short-term with an increase in the peak 1 signal value which is consistent with an increase in stiffness of cornea, whereas IOPcc, CRF and CH values remained the same.

How to cite this article

Klllç A, Roberts CJ. Biomechanical and Refractive Results of Transepithelial Cross-linking Treatment in Keratoconic Eyes. Int J Kerat Ect Cor Dis 2012;1(2):75-78.


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